Nobel Laureate Lecture: Venkatraman Ramakrishnan (MRC Laboratory of Molecular Biology, Cambridge, United Kingdom), Nobel Prize in Chemistry 2009 for studies of the structure and function of the ribosome.

The use of recent advances in electron microscopy to study ribosome structures
For the last hundred years, the main technique to determine the atomic structures of molecules has been X-ray crystallography. Recently, advances in both detectors and algorithms for data analysis has made it possible to reach ~3 Å resolution using single-particle electron microscopy. This has for the first time made it possible to obtain atomic models of large macromolecules without the use of crystals and with very small amounts and heterogeneous samples. I will discuss how my laboratory has used these advances to determine an atomic model for the large mitochondrial ribosomal subunit de novo.


Mois Aroyo
Universidad del Pais Vasco
Bilbao, Spain

Alessia Bacchi
University of Parma
Parma, Italy

Vladislav Blatov
Samara State University
Samara, Russia

Gervais Chapuis
École Polytechnique Fédérale de Lausanne
Lausanne, Switzerland

Carmelo Giacovazzo
CNR-Istituto di Cristallografia
Bari, Italy

Cinzia Giannini
CNR-Istituto di Cristallografia
Bari, Italy

Santiago García Granda
University Oviedo-CSIC-PA
Oviedo, Spain

Antonella Guagliardi
CNR-Istituto di Cristallografia
Como, Italy

Christian Jelsch
CNRS and Jean Barriol Institute
Université de Lorraine
Nancy, France

Claude Lecomte
CNRS and Jean Barriol Institute
Université de Lorraine
Nancy, France

Brian McMahon
International Union of Crystallography
Chester, United Kingdom

Lukáš Palatinus
Institute of Physics
Czech Academy of Sciences
Prague, Czech Republic

Ludovico Pernazza
University of Pavia
Pavia, Italy

Stanko Popović
University of Zagreb
Zagreb, Croatia

Juliette Pradon
Cambridge Crystallographic Data Center
Cambridge, United Kingdom

Davide Proserpio
University of Milan
Milan, Italy

Randy J. Read
Cambridge Institute for Medical Research
Cambridge, United Kingdom

Emanuela Schingaro
University of Bari
Bari, Italy

Thomas Schneider
European Molecular Biology Laboratory
Hamburg, Germany

Consiglia Tedesco
University of Salerno
Salerno, Italy

Giuseppe Zanotti
University of Padua
Padua, Italy



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28 February 2014
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Notification of selections:
The selection committee has concluded the evaluation of the unexpectedly large number of applications received. Candidates will start receiving the results from next week onwards.

Abstract submission:
16 June 2014

16 June 2014